Pheromonal Compounds and Histological Alteration of Castrated Mose Preputial Gland in Relation to Eruca Sativa Extract

"This study included the effects of 3mg/kg/day of Eruca sativa on:
Melanocortin-5-receptor (MC5R); * Total lipid compounds, * Essential pheromonal compounds and * The Histological structure of the castrated mice preputial glands for 42 days of treatment were investigated.
This treatment is resulted in:
A- A significant increase of MC5R level in preputial gland of castrated treated animals with Eruca sativa as compared with the control group (P<0.01).
B- It has marked effects on the: total lipid compounds, essential pheromonal compounds and histological restoration of the preputial gland structures in castrated treated subjects.
C- This treatment was able to restore four compounds (out of six) of the essential pheromones which are:
1- α.-Farnesene and (E)-α. - Farnesene
2- (1-Tetradecanol)
3- Tetradecanol acetate)
4- (1- Hexadecanol acetate).
D- Eruca sativa revealed was able to restore the gland activity.

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