Glanzmann’s Thrombasthenia: Report of A Case and Review of the Literature

Thankam, Thamari and John, Ashnah (2024) Glanzmann’s Thrombasthenia: Report of A Case and Review of the Literature. International Journal of Life Sciences, 13 (2). pp. 38-40. ISSN 2277-193x

[thumbnail of Research Article] Text (Research Article)
Article_IJLS_10-04-2024.pdf - Published Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (290kB)

Abstract

Glanzmann’s thrombasthenia (GT)is a rare autosomal recessive disorder characterized by qualitative or quantitative abnormalities of the platelet membrane glycoprotein (GP) IIb/IIIa. These integrins are encoded by the ITGA2B and ITGB3 genes and form platelet glycoprotein (GP)IIb/IIIa, which acts as the principal platelet receptor for fibrinogen. Spontaneous mucocutaneous bleeding is common and can lead to fatal bleeding episodes.

Item Type: Article
Uncontrolled Keywords: Glanzmann’s thrombasthenia ,Glycoprotein, platelet, bleeding.
Subjects: R Medicine > RT Nursing
Divisions: Department of Community Health Nursing > Research papers
Depositing User: ePrints Editor
Date Deposited: 21 Aug 2025 17:38
Last Modified: 21 Aug 2025 17:38
URI: https://eprints.cihanuniversity.edu.iq/id/eprint/4452

Actions (login required)

View Item
View Item