Ocular Drug Delivery System: An Overview

The scientist faced many challenges in Ocular drug delivery
system due to unique anatomy and physiology of eye. In ocular drug delivery system there are two types of barriers static and dynamic barrier. Static barriers consist of different segment of eye such as cornea, sclera, retina and blood- retinal barriers. In other way dynamic barriers consists choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution. These both barriers affect the bioavailability of drugs. In recent year some new concept of drug delivery such as iontophoresis, liposome
bioadhesive gels, ocular insert, contact lenses etc has been developed to overcome problems associated by static and
dynamic barriers These formulation based approaches have high capacity to carry maximum concentration of drug at targeted site of eye.