Interleukin-6 Levels in Relation to COVID-19 Vaccine

SARS COV-2 is a pulmonary disease known as COVID -19 that has been infecting people since late December 2019 and continues to cause organ failure due to elevated cytokines and chemokines causing cytokine storm syndrome, elevating levels of Interleukin-6 and lactate dehydrogenase enzyme (LDH). In this study, a total of 120 cases were included that were collected in Cihan University-Erbil Campus from October to November 2021. In these 120 samples, categorized into four different groups (NN, CN, NV and CV) N is for non-vaccinated, C is for COVID-19 and V is for vaccinated, each group consisting of 30 cases. The study found that those who had COVID-19 infection and were vaccinated had much greater levels of interleukin 6 than the other groups. COVID-19 causes IL-6 to rise, but immunization doubles the level. Furthermore, the serum samples taken from them for lactate-dehydrogenase LDH test, the study showed that both COVID-19 infection and vaccination will cause a massive increase in LDH level in the body. Lastly, there were hematological parameters for the samples which indicated that those who got COVID-19 infection their WBC and monocyte were increased compared to those who got vaccinated which was significantly increased. The study did a platelet test for the samples, but there was no significant difference between the groups.