Serum Level of Osteopontin Associated With Heart Disease in Iraqi Male

Background: Heart disease is a serious health-care
issue in males and females, with high morbidity, death, and costs
.Men had a higher chance of developing Heart disease, whereas
women were leaser than .
Aim: Osteopontin (OPN) activity was measured by comparing
heart disease patients and healthy control subjects in this research.
It is critical to use biochemical markers as reliable predictors.
Osteopontin biochemical factors in patients with heart disease was
assessed and their relationships studied as a result.
Methods: Blood samples were collected from 90 male persons, age
range (40-62) years, in Ibn Al-Bitar Hospital for Cardiac Surgery.
The subjects was been divided into two groups (60 patients with
heart disease and 30-control group). The participants' ages and
BMIs were tallied, estimates the lipid profile levels by enzymatic
method,and the ELISA technique was used to assess osteopontin
levels.
Results: the study appeared a significant difference between the
levels of osteopontin in patients and those of healthy individuals.
The data showed that HDL levels were statistically different
between the sick and healthy groups (p<0.05) in terms of age, BMI,
cholesterol, TGs, LDL, and VLDL levels.).
Conclusion: Using OPN as a marker for early identification of
heart disease was shown to be effective in this study. According to
the findings, OPN is the most useful biomarker for the early
detection of cardiovascular disease.