Assessment of the Correlation of Lipasin Levels with HOMA-IR Score as an Index of Insulin Resistance in Type 2 Diabetic Iraqi Patients

Lipasin, a hormone found in the liver and adipose tissue, is involved in glucose homeostasis and lipid metabolism. Lipasin levels in plasma are controlled by food and rise after glucose consumption. Because plasma glucose and insulin levels both rise after eating, we wanted to know if the rise in plasma insulin sensitivity, or both, is to blame for the rise in lipasin levels. According to this study, the patient group's lipasin concentration increased significantly (p-value˂ 0.05) in comparison to the control group, and the area under the curve (AUC) for lipasin was 75.75 %. As well, the levels of insulin and glucose and also for the BMI there was a significant difference (p- value˂ 0.05) between the studied groups. The results emphasize that Lipasin may play a crucial role in T2DM development.