Efficacy and Safety of Oral Isotretinoin and non Insulated Fractional Microneedling Radiofrequency in Acne Treatment.

Non isulated microneedling RF can be used for treatment of pilosebaceous unit disorders especially in age 11-30 years who have acne vulgaris with oral therapy of isotretinoin. The psychosocial impact of acne that have affected individuals have doubtless social bleakness and many psychological disturbance. Aim: Efficacy and Safety of combined non insulated fractional microneedling radiofrequency (NIFMNRF) with oral isotretinoin drug in treatment of acne. Material and methods: A study that include Forty eight patients with acne (moderate to severe) were subjected to monthly sessions of fractional RF micro-needling device (4 times) and oral isotretinoin therapy 0.5–1 mg/kg for 5 five months. Results: In this research, 48 acne vulgaris were evaluated for 6 months duration received 20-40mg of oral isotretinion and 4 monthly session of NIFMNRF. Acne vulgaris patients were 20.6 ±3.3 years old, 55.85 ±5.6 kg, 40 females, and 8 males. After 12 weeks all patients shows better global acne assessment scale (GAAS) result. The global acne assessment scale change with every months of treatment. Age or weight doesn’t have difference and no permanent side effect of scarring or hypo and hyperpigmentation due to use of NIFMFRF even in type III & IV skin type and patient have high satisfaction for this combination of treatment. Conclusion: from the present study show that the combination of NIFMNRF with concomitant use of oral therapy of isotretinion in treatment of moderate to severe acne are highly effective with less scarring and high satisfaction result.