Hussen, Bashdar Mahmud Hussen and Hussen, Bashdar Mahmud and Abdullah, Snur Rasool and Fatih Rasul, Mohammed and Hajiesmaeili, Yasaman and Baniahmad, Aria and Taheri, Mohammad (2024) Advanced Approaches of the use of CircRNAs as a Replacement for Cancer therapy. Non-coding RNA Research, 9 (3). pp. 811-830. ISSN 24680540
![[thumbnail of Research Articale]](https://eprints.cihanuniversity.edu.iq/style/images/fileicons/text.png)
Articale_N_C_R_R_04-03-2024.pdf - Published Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.
Download (11MB)
Abstract
Cancer is a broad name for a group of diseases in which abnormal cells grow out of control and are characterized by their complexity and recurrence. Although there has been progress in cancer therapy with the entry of precision medicine and immunotherapy, cancer incidence rates have increased globally. Non-coding RNAs in the form of circular RNAs (circRNAs) play crucial roles in the pathogenesis, clinical diagnosis, and therapy of different diseases, including cancer. According to recent studies, circRNAs appear to serve as accurate indicators and therapeutic targets for cancer treatment. However, circRNAs are promising candidates for cutting-edge cancer therapy because of their distinctive circular structure, stability, and wide range of capabilities; many challenges persist that decrease the applications of circRNA-based cancer therapeutics. Here, we explore the roles of circRNAs as a replacement for cancer therapy, highlight the main challenges facing circRNA-based cancer therapies, and discuss the key strategies to overcome these challenges to improve advanced innovative therapies based on circRNAs with long-term health effects.
Item Type: | Article |
---|---|
Uncontrolled Keywords: | CancerCancer therapyCirc RNAsChallenges Strategies |
Subjects: | B Philosophy. Psychology. Religion > B Philosophy (General) R Medicine > R Medicine (General) |
Divisions: | Department of Biomedical Science > Research papers |
Depositing User: | ePrints Depositor |
Date Deposited: | 20 Nov 2024 13:13 |
Last Modified: | 20 Nov 2024 13:13 |
URI: | https://eprints.cihanuniversity.edu.iq/id/eprint/2919 |